Nicholas broke it down for us, step by step. “First, it requires an empty, clean syringe. With the empty syringe, you remove the plunger (the part you push) and place the medication in the syringe. Next, you put the plunger back on, remove all air from the syringe, and draw up as much fluid as you need to mix the medication in. This amount of fluid will depend on which medication you are administering,” he explained.